interferon

How influenza virus infection might lead to gastrointestinal symptoms

2 Comments / Basic virology, Information / By

Human influenza viruses replicate almost exclusively in the respiratory tract, yet infected individuals may also have gastrointestinal symptoms such as vomiting and diarrhea. In mice, intestinal injury occurs in the absence of viral replication, and is a consequence of viral depletion of the gut microbiota. Intranasal inoculation of mice with the PR8 strain of influenza virus leads …

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Thirty years in my laboratory at Columbia University

8 Comments / Basic virology, Information / By

Thirty years ago this month I arrived in the Department of Microbiology at Columbia University’s College of Physicians and Surgeons (P&S) to start my own laboratory. Thirty is not only a multiple of ten (which we tend to celebrate), but also a long time to be at one place. It’s clearly time to reminisce! After …

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TWiV 153: Rabid reindeer and protective prions

This Week in Virology / By

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Vincent, Alan, and Rich review an outbreak of rabies in arctic foxes and reindeer in Norway, and a prion that makes you go antiviral. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV153.mp3″] Click the arrow above to play, or right-click to download TWiV 153 (55 MB .mp3, 92 minutes). Subscribe to TWiV (free) in …

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