interferon

TWiV 412: WO, open the borders and rig the infection

The TWiVome reveal the first eukaryotic genes found in a bacteriophage of Wolbachia, and how DNA tumor virus oncogenes antagonize sensing of cytoplasmic DNA by the cell. You can find TWiV #412 at microbe.tv/twiv, or listen below. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV412.mp3″] Click arrow to play Download TWiV 412 (73 MB .mp3, 121 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV!

A new function for oncoproteins of DNA tumor viruses

Oncogenes of DNA tumor viruses encode proteins that cause cells to divide incessantly, eventually leading to formation of a tumor. These oncoproteins have now been found to antagonize the innate immune response of the cell (link to paper). Most cells encountered by viruses are not dividing, and hence do not efficiently support viral DNA synthesis. The …

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TWiV 392: Zika virus!

Four virologists discuss our current understanding of Zika virus biology, pathogenesis, transmission, and prevention, in this special live episode recorded at the American Society for Microbiology in Washington, DC. You can find TWiV #392 at microbe.tv/twiv, or listen/watch below. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV392.mp3″] Click arrow to play Download TWiV 392 (62 MB .mp3, 85 min) Subscribe (free): iTunes, RSS, email, Google …

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TWiV 382: Everyone’s a little bit viral

On episode #382 of the science show This Week in Virology, Nels Elde and Ed Chuong join the TWiV team to talk about their observation that regulation of the human interferon response depends on regulatory sequences that were co-opted millions of years ago from endogenous retroviruses. You can find TWiV #382 at microbe.tv/twiv, or listen below. [powerpress …

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TWiV 336: Brought to you by the letters H, N, P, and Eye

On episode #336 of the science show This Week in Virology, the TWiVsters explore mutations in the interferon pathway associated with severe influenza in a child, outbreaks of avian influenza in North American poultry farms, Ebolavirus infection of the eye weeks after recovery, and Ebolavirus stability on surfaces and in fluids. You can find TWiV …

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