One and Done
…cleavage by furin. The FDA’s decision to issue an emergency use authorization for Ad26.COV2.S was based on safety and efficacy data from an ongoing Phase III clinical trial done…
Search Results for: Trial by Error
Herpes simplex virus and Alzheimer€™s disease
…linked to Alzheimer€™s Disease (AD), and a clinical trial is in progress to determine if antivirals ameliorate its development. What is the evidence that HSV-1 is involved in AD? HSV-1…
A Pill to Prevent Gastroenteritis
…norovirus-induced illness. Nevertheless, recent developments in this field have led to remarkable and promising new advances. A phase 1b clinical trial has revealed that a norovirus vaccine candidate is safe…
Jonas Salk’s Poliovaccine
…clinical trial of IPV were announced. The trial, supported by the National Foundation for Infantile Paralysis (NFIP) and organized by Thomas Francis of the University of Michigan, involved 1.8 million…
At least we’re not vexatious
On 17 December 2015, Ron Davis, Bruce Levin, David Tuller and I requested trial data from the PACE study of treatments for ME/CFS published in The Lancet in 2011. Below…
First efficacy results of a COVID-19 vaccine candidate
…The term ‘efficacy’ is used when a study is carried out under ideal conditions, for example, during a clinical trial. Vaccine effectiveness is used when a study is carried out…