A controlled trial of face masks for COVID-19
…been tested in the Bangladeshi trial. The face mask trial was carried out in rural Bangladesh from November 2020 to April 2021. It enrolled 342,183 adults in 600 villages and…
Search Results for: Trial by Error
Increased fidelity reduces viral fitness
We have spent over a week discussing the effects of polymerase error rates on viruses. RNA viruses have the highest error rates in nature, a property that is believed to…
Viral variation in single cells
…carry out error-prone replication to adapt to new environments. A consequence is that RNA virus populations exist close to an error threshold beyond which infectivity is lost. How the balance…
Novartis influenza A H1N1 vaccine clinical data
…been approved for use in the US. A media release is no substitute for revealing clinical trial results in a peer-reviewed scientific journal. Novartis indicates that the vaccine trial will…
A Long-Awaited Vaccine
…RSV F antigen and the adjuvant are supplied separately and combined prior to administration of the mixture as a single intramuscular injection. Phase III clinical trials engaging 25,000 adults over…
H5N1 expert says ‘The virus is definitely mutating’
…error-prone nucleic acid polymerases. The error rate for RNA virus genomes is phenomenal, because the viral polymerases cannot correct its mistakes. The error rates for viral RNA-dependent RNA polymerases have…