Poliovirus by Jason Roberts The global withdrawal of the Sabin type 2 poliovirus vaccine is a test of the feasibility of the plan, declared by the World Health Assembly in 1988, to eradicate all polioviruses. The main vaccine used for the poliovirus eradication effort is an infectious, attenuated preparation called ...

The TWiV team considers whether those who can do, can't teach, and newly discovered viruses of planarians and Aplysia with the largest RNA genomes. <span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"></span><span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"></span><span data-mce-type="bookmark" style="display: inline-block; width: 0px; ...

The development of high throughput nucleic acid sequencing tools has rapidly increased the pace of virus discovery in the past 20 years. Yet in that time, while the largest DNA genomes have increased by nearly ten times, the largest known RNA viral genome has only increase in size by a ...

Jens Kuhn returns to present a brief history of bioweapons, with a focus on the program in the Soviet Union, the largest ever undertaken, and his experience working in the decommissioned Soviet bioweapons laboratory known as Vector. <span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"></span>&lt;span data-mce-type="bookmark" style="display: ...

Glucose metabolism. After transport into cells via glucose transporters (Gluts) and phosphorylation by hexokinase, glucose can enter glycolysis or the pentose phosphate pathway for nucleotide synthesis. Glycolysis produces 2 molecules of pyruvate from 1 of glucose, with a net energy yield of 2 ATP and 2 NADH. Image credit. Viral ...