John Coffin, Professor of Genetics and Molecular Microbiology at Tufts University, studies the molecular biology and evolution of retroviruses. He wrote a commentary (A new virus for old diseases?) that accompanied the publication by Lombardi and colleagues of the finding of the new retrovirus XMRV in patients with chronic fatigue ...

Many virological techniques are based on the specificity of the antibody-antigen reaction. Examples in our virology toolbox include western blot analysis and ELISA. While very useful, these methods cannot be used to visualize viral proteins in infected cells or tissues. To do that we must turn to immunostaining. In direct ...

Now that we have reached the 100th episode of TWiV, I'd like to ask our listeners a question that I have been pondering for the past 50 episodes: Is a weekly virology podcast too much? I have the feeling that most listeners don't have the time to hear every episode, ...

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and David Baltimore Vincent, Alan, and Rich celebrate the 100th episode of the podcast This Week in Virology by talking about viruses with Nobel Laureate David Baltimore. [powerpress url="http://traffic.libsyn.com/twiv/TWiV100.mp3"] Click the arrow above to play, or right-click to download TWiV #100 (68 MB ...

All known virus particles can be placed into one of two general categories: enveloped or non-enveloped. Viruses that fall into the former category are characterized by a lipid membrane derived from the host cell, and one or more nuclecapsid proteins that interact with the viral genome. A virus that infects ...