Virology
A request for data from the PACE trial
By Vincent Racaniello
Mr. Paul Smallcombe Records & Information Compliance Manager Queen Mary University of London Mile End Road London E1 4NS Dear Mr Smallcombe: The PACE study of treatments for ME/CFS has been the source of much controversy since the first results were published in The Lancet in 2011. Patients have repeatedly raised objections ...
TWiEVO: This Week in Evolution
By Vincent Racaniello
To a molecular biologist, the word 'evolution' evokes images of fossils, dusty rocks, and phylogenetic trees covering eons. The fields of molecular biology and evolutionary biology diverged during the twentieth century, but new experimental technologies have lead to a fusion of the two disciplines. The result is that evolutionary biologists have the unprecedented ability to evaluate ...
TWiV 367: Two sides to a Coyne
By Vincent Racaniello
On episode #367 of the science show This Week in Virology, two Coynes join the TWiV overlords to explain their three-dimensional cell culture model of polarized intestinal for studying enterovirus infection. You can find TWiV #367 at www.microbe.tv/twiv.
Exaptation: A cell enzyme becomes a viral capsid protein
By Vincent Racaniello
The acquisition of a capsid is thought to be a key event in the evolution of viruses from the self-replicating genetic elements that existed during the pre-cellular stage on Earth. The origin of viral capsids has been obscure because their components are not similar to cellular proteins. The discovery that a ...
TWiV 366: Doctorates down under
By Vincent Racaniello
On episode #366 of the science show This Week in Virology, Vincent visits Melbourne, Australia, where he speaks with four PhD students about their research projects and what it's like to get a doctorate down under. You can find TWiV #366 at www.microbe.tv/twiv. Or you can watch the video below.