An Intranasal SARS-CoV-2 Vaccine Candidate
Intranasal administration with a single dose of a chimpanzee adenovirus-vectored SARS-CoV-2 vaccine induces potent immune responses.
vaccine
TWiV 871: If the ACE2 fits, ferret
TWiV discusses whether or not Omicron should be designated a new serotype of SARS-CoV-2, and the finding that amino acid changes that adapt SARS-CoV-2 to mink or ferret do not increase fitness in the human airway.
TWiV 870: COVID-19 clinical update #103 with Dr. Daniel Griffin
In COVID-19 clinical update #103, Daniel Griffin covers immunocompromised people, hospitalization of children, vaccine usage update, Omicron and cross-reactive neutralizing antibodies, reinfection prevents disease in hamsters, repeated infections with endemic coronaviruses, global burden of antimicrobial resistance, ivermectin not protective in hamsters, and Omicron evades therapeutic monoclonals. Click arrow to playDownload TWiV 870 (52 MB .mp3, 43 …
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TWiV 868: COVID-19 clinical update #102 with Dr. Daniel Griffin
In COVID-19 clinical update #102, Daniel Griffin reviews children and COVID, effectiveness of maternal vaccination, vaccines for immunocompromised, primary care physicians and vaccination rates, booster safety among adults, placentitis, azithromycin, oral Nirmatrelvir, Omicron antibody evasion, EUA for bebtelovimab, IL-1 blocking agents, thromboprophylaxis, effectiveness of vaccines against long COVID, and risks of mental health outcomes.
TWiV 867: I love the smell of vaccines in the morning
TWiV reviews an experimental, intranasally administered SARS-CoV-2 vaccine that utilizes adenovirus vectors to deliver three viral proteins and induces immunity to ancestral and variant isolates. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler Click arrow to playDownload TWiV 867 (128 MB .mp3, 107 min)Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv
Paul’s Uncle Doesn’t Want to Get Vaccinated
From the authors of Paul Has Measles, Paul Stays Home, and Paul and the Mosquitos, comes Paul’s Uncle Doesn’t Want to Get Vaccinated, an illustrated book for children about vaccines and vaccine hesitancy. Uncle Henry doesn’t want to get vaccinated against COVID-19. Paul, Sophie, and Luis are afraid that he will get sick, so they show him …