When live, attenuated poliovirus vaccine was used in the US, its production and testing was regulated by the Food and Drug Administration. Guidelines for preparing and testing the vaccine can be found in the Code of Federal Regulations – the codification of the rules published in the Federal Register by the executive departments and agencies …
If you are not convinced that vaccines are safe, please listen to a conversation between Dr. Ginger Campbell of the Brain Science Podcast and Dr. Paul Offit. Dr. Offit is a pediatrician who is also Chief of Infectious Diseases and Director of Vaccine Education at the University of Pennsylvania School of Medicine. He is co-developer …
The best way to prevent influenza is by immunization. Unlike vaccines for polio and measles, which confer life-long immunity, the influenza vaccine protects for only one year. Influenza virus undergoes antigenic variation, necessitating annual production of a new vaccine. Is it possible to formulate an influenza vaccine that protects against all virus strains for life? Two studies …
Influenza virus undergoes continuous antigenic variation, necessitating production of a new vaccine each year. This is not a trivial task. Six to nine months before the flu season begins, the viral strains for inclusion in the vaccine must be selected. High-yielding recombinant strains are produced and grown in embryonated chicken eggs. This year, approximately 140 …
Vincent and Jeremy recorded TWiV #16 in Saanen, Switzerland, at the 19th Challenge in Virology. They review the meeting, and discuss implications of a new HIV-1 sequence from 1960 for the origin of AIDS. Click the arrow above to play, or right-click to download TWiV #16
Poliovirus is the etiologic agent of the paralytic disease known as poliomyelitis. It’s also the virus I’ve worked on for most of my career. The World Health Organization is in the midst of a massive effort to eradicate the disease, an undertaking that has encountered a number of obstacles. In coming posts I’d like to …
