From the EIDA2Z conference at Boston University, Vincent, Alan and Paul meet up with Ralph Baric, Felix Drexler, Marion Koopmans, and Stacey Schultz-Cherry to talk about discovering, understanding, protecting, and collaborating on emerging infectious diseases. You can find TWiV #413 at microbe.tv/twiv, or watch or listen here. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV413.mp3″] Click arrow to play Download TWiV 413 (44 MB …
The TWiV team takes on an experimental plant-based poliovirus vaccine, contradictory findings on the efficacy of Flumist, waning protection conferred by Zostavax, and a new adjuvanted subunit zoster vaccine. You can find TWiV #403 at microbe.tv/twiv, or listen below. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV403.mp3″] Click arrow to play Download TWiV 403 (70 MB .mp3, 96 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV!
Although the use of the live, attenuated (Sabin) poliovirus vaccines has been instrumental in nearly eradicating the virus from the planet, the rare reversion to virulence of these strains has lead to the World Health Organization to recommend their replacement with inactivated poliovirus vaccine (IPV). Unfortunately IPV is also not without shortcomings, including high cost, failure …
Whole plant cells producing viral capsid protein as a poliovirus vaccine candidate Read More »
Polio returns to Nigeria, Zika virus spreads in Miami, and virus infection of plants attracts bumblebees for pollination, from the virus gentlepeople at TWiV. You can find TWiV #400 at microbe.tv/twiv, or listen below. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV402.mp3″] Click arrow to play Download TWiV 402 (85 MB .mp3, 118 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV!
Zika virus spreads in the USA, a Zika virus DNA vaccine goes into phase I trials, and how mosquito bites enhance virus replication and disease, from the friendly TWiFolk Vincent, Dickson, Alan, and Kathy. You can find TWiV #401 at microbe.tv/twiv, or listen below. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV401.mp3″] Click arrow to play Download TWiV 401 (86 MB .mp3, 119 min) Subscribe (free): iTunes, RSS, email …
Flaviviruses are unusual because antibodies that cross-react with different viruses can enhance infection and disease. This property, called antibody-dependent enhancement or ADE, has been documented to occur among the four serotypes of dengue virus. It has implications for infection with or vaccination against Zika virus or dengue virus. Earlier this year (virology blog link) it was …
