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The Lazarus virus

There is an excellent question in the comments to “Are all virus particles infectious?“: if the particle-to-PFU ratio for a virus stock is 10,000:1, and I infect 1,000,000 cells with 10,000 particles, how many plaques would I expect to observe? Answering this question provides insight into the particle-to-PFU ratio of viruses. If we take 10,000 particles …

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TWiV 129: We’ve got mail

Hosts: Vincent Racaniello, Alan Dove, Dickson Despommier, and Rich Condit Vincent, Alan, Dickson and Rich answer listener questions about XMRV, yellow fever vaccine, virus-like particles, West Nile virus, amyotrophic lateral sclerosis and human endogenous retroviruses, multiplicity of infection, and how to make a poxvirus. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV129.mp3″] Click the arrow above to play, or right-click to download …

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TWiV 118: The virus always rings twice

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit On episode #118 of the podcast This Week in Virology, Vincent, Alan, and Rich answer listener questions about vaccinia virus, fungal viruses, synthetic viruses, influenza vaccine, HeLa cells, multiplicity of infection, and much more. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV118.mp3″] Click the arrow above to play, or right-click to download TWiV #118 (68 …

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