lentivirus

CRISPR-ing HIV-1

By Gertrud U. Rey Although antiretroviral therapy (ART) has been highly effective at controlling HIV-1 viral loads in the bloodstream of infected individuals, the virus remains latent in infected cells and starts replicating within a couple of weeks upon termination of therapy.

TWiV 204: M m m my corona

On episode #204 of the science show This Week in Virology, Vincent, Alan, Matt and Kathy review isolation of a new coronavirus from two patients in the Middle East, and expansion of the enteric virome during simian AIDS. You can find TWiV #204 at www.microbe.tv/twiv.

Clinical benefit of lentiviral gene therapy in two patients with a rare neurologic disease

X-linked adrenoleukodystrophy (ALD) is a rare neurologic disease caused by a defect in a gene required for normal ABCD1 transporter function. The lack of this function leads to progressive demyelination, severe neurologic disease and death in males, often in childhood. ALD disease progression can be controlled by allogeneic hematopoietic cell transplantation (HCT) in those patients …

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TWiV # 12: Prions in milk, lemur lentiviruses, RS virus vaccine, H5N1

This Week in Virology #12 has been posted at twiv.tv. Click the arrow above to play, or right-click to download TWiV #12 In this episode, Vincent, Alan, and Angela discuss Kuru, prions in milk, ancient lentiviruses found in the chromosomes of lemurs, a respiratory syncytial virus vaccine failure in the 1960s, and recent outbreaks of H5N1 …

TWiV # 12: Prions in milk, lemur lentiviruses, RS virus vaccine, H5N1 Read More »

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