Kartik Chandran and Rohit Jangra join the TWiV team to present their identification of protocadherin-1 as a cell receptor for New World hantaviruses. Click arrow to play Download TWiV 549 (62 MB .mp3, 103 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv
Virus particles are metastable: they must be highly stable, to protect the nucleic acid while traveling from host to host or cell to cell, and then come apart to liberate the genome into the cell. New insight into this uncoating process comes from beautiful images of feline calicivirus showing formation of a portal on the …
The TWiVsters describe a new animal model for MERS coronavirus-induced acute respiratory distress syndrome, produced by CRISPR/Cas9 editing of the mouse gene encoding an ortholog of the virus receptor. You can find TWiV #418 at microbe.tv/twiv, or listen below. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV418.mp3″] Click arrow to play Download TWiV 418 (63 MB .mp3, 104 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV!
The TWiVeroos examine a reverse spillover of Newcastle disease virus vaccines into wild birds, and identification of a protein cell receptor for murine noroviruses. You can find TWiV #411 at microbe.tv/twiv, or listen below. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV411.mp3″] Click arrow to play Download TWiV 411 (59 MB .mp3, 95 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV!
The TWiV team discusses eye infections caused by Zika virus, failure of Culex mosquitoes to transmit the virus, and replication of norovirus in stem cell derived enteroids. You can find TWiV #406 at microbe.tv/twiv, or listen below. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV406.mp3″] Click arrow to play Download TWiV 406 (59 MB .mp3, 98 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV!
Rhinovirus is the most frequent cause of the common cold, and the virus itself is quite common: there are over 160 types, classified into 3 species. The cell receptor has just been identified for the rhinovirus C species, which can cause more severe illness than members of the A or B species: it is cadherin-related family …
