Pushing viruses over the error threshold
…error threshold because it causes the RNA polymerase to make more errors than it already does. What would be the property of a poliovirus mutant resistant to this drug? A…
Search Results for: Trial by Error
My letter to organizer of 4th Columbia Psychosomatics Conference
…Tuller used a phrase that he later decided was inappropriate, and he removed it from his “Trial By Error” post. I have done the same in quoting his response here….
Once Again, Lancet Stumbles on PACE
…should justify itself based on the uninterpretable findings of the PACE trial. The MAGENTA trial should be halted until the PACE authors have done what the First-Tier Tribunal ordered them…
The error-prone ways of RNA synthesis
…about one misincorporation per 107 to 109 nucleotides polymerized. But the RNA polymerases of RNA viruses are the kings of errors – these enzymes screw up as often as one…
Trial By Error, Continued: The CMRC Affirms Full Support for Libelous Esther
By David Tuller, DrPH For the last couple of weeks, I have been hammering the CFS/ME Research Collaborative to take a position on the actions of its deputy chair, Libelous…
Trial by Error: NICE Declines to Disclose Names of Experts
By David Tuller, DrPH The Countess of Mar, a well-known advocate for ME/CFS patients in the House of Lords, has received a negative response to her request for the names…