David Tuller’s Fundraiser
…not just irrational patients, had serious concerns about the PACE trial. The court ordered the release of the raw trial data, which has proven what patients have known all along…
Search Results for: Trial by Error
A SARS-CoV-2 Vaccine Candidate
…since the trial participants were immunized. Because SARS-CoV-2 is considered a dangerous pathogen, traditional challenge trials, in which an immunized individual is intentionally infected with the pathogen against which he…
An Ebolavirus vaccine in Africa
…The results of Phase I trials of rVSV-EBOV in Africa (Gabon, Kenya) and Europe (Hamburg, Geneva) were published on 1 April 2015. These trials comprised three open-label, dose-escalation trials, and…
Preliminary phase I/II results of ChAdOx1 SARS-CoV-2 vaccine
by Gertrud U. Rey On July 20, 2020, Oxford University’s Jenner Institute and the pharmaceutical company AstraZeneca reported preliminary results from phase I/II clinical trials assessing the safety and efficacy of…
The AstraZeneca/Oxford University Phase 3 COVID-19 Vaccine Trial €“ Why Was It Paused?
…(2020). https://www.statnews.com/2020/09/09/astrazeneca-covid19-vaccine-trial-hold-patient-report/. Levin NA, Kivity S, Szyper-Kravitz, Shoenfeld Y. Transverse myelitis and vaccines: a multi-analysis. Lupus. (2009) 18: 1198-1204. Loftus P. AstraZeneca COVID-19 Vaccine Trials Resume in U.K. WSJ. (2020). https://www.wsj.com/articles/astrazeneca-covid-19-vaccine-trials-resume-in-the-u-k-11599922981….
Pushing viruses over the error threshold
…error threshold because it causes the RNA polymerase to make more errors than it already does. What would be the property of a poliovirus mutant resistant to this drug? A…