…Times and The BMJ covered the growing international concerns about the PACE trial. Both publications ran articles about Virology Blog’s most recent open letter to The Lancet, which cited PACE’s…
…grasp that unblinded trials relying on self-reported outcomes, like PACE, are so fraught with bias as to be uninterpretable. That’s why clinical trials with this design are never used as…
…our trial of treatments for chronic fatigue syndrome, published recently in The Lancet. That is not the case. The patients in this trial had a disabling chronic illness in which fatigue…
…it was, in fact, designed as a fully powered trial. The investigators suggested in their conclusions that the results “might justify a full-scale clinical trial”, even though they had just…
…alone. The trial’s primary outcome was the mean score on the Work and Social Adjustment Scale (WSAS) at follow-up assessment 52 weeks post-randomization. The trial also included several secondary outcomes….
…a proposed LP trial until at least June. The trial has already been approved by a regional committee. The NEM had been expected to decide at its May meeting but…
