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A transmissible cancer of soft-shell clams

A leukemia-like cancer is killing soft-shell clams along the east coast of North America. The cancer is transmitted between animals in the ocean, and appears to have originated in a single clam as recently as 40 years ago. Hemic neoplasm is a disease of marine bivalves that is characterized by proliferation of morphologically and functionally aberrant hemocytes, the …

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Infectious agents with no genome

If the reader does not believe that viroids and satellites are distinctive, then surely prions, infectious agents composed only of protein, must impress. The question of whether infectious agents exist without genomes arose with the discovery and characterization of infectious agents associated with a group of diseases called transmissible spongiform encephalopathies (TSEs). These diseases are …

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Reconstruction of 1918-like avian influenza virus stirs concern over gain of function experiments

The gain of function experiments in which avian influenza H5N1 virus was provided the ability to transmit by aerosol among ferrets were met with substantial outrage from both the press and even some scientists; scenarios of lethal viruses escaping from the laboratory and killing millions proliferated (see examples here and here). The recent publication of …

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