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Hand hygiene removes influenza virus

Dispensers of alcohol-based rubs are appearing in public places in an attempt to reduce the spread of pandemic influenza. Are these effective at removing virus from hands? In a recent study, the hands of twenty vaccinated, antibody-positive volunteers were contaminated with 10,000,000 TCID50 of a 1999 seasonal H1N1 influenza virus strain (see this post for …

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Virulence: A positive or negative trait for evolution?

With just 141 confirmed deaths so far, an interesting question is whether the 2009 H1N1 influenza virus could mutate into something more lethal (“How a Mild Virus Might Turn Vicious“). Of course it could – but is it beneficial for the virus? A fundamental principle of viral evolution is that viruses must spread from host …

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WHO will redefine pandemic

The World Health Organization, whose duties include directing and coordinating authority for health within the United Nations system, will soon be writing science textbooks. That statement isn’t true, of course. But it was my reaction to reading the latest announcement from Geneva: Bowing to pressure, the World Health Organization announced Friday that it would rewrite its rules for …

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TWiV 32: Influenza in silico

On episode #32 of the podcast This Week in Virology, Vincent, Alan, and Raul Rabadan converse about polio survivors in iron lungs, bocavirus, structure of mimivirus, and genome sequence analysis of influenza H1N1 viruses. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV032.mp3″] Click the arrow above to play, or right-click to download TWiV #32 or subscribe in iTunes or by email.

Influenza A/Mexico/2009 (H1N1) virulence and transmission

The influenza H1N1 outbreak in Mexico has been analyzed to provide information on the pandemic potential of the new virus strain. The estimates offer some insight into the transmissibility and severity of the virus but must be tempered with the understanding that there are still uncertainties about all aspects of the outbreak. Influenza incidence is …

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