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By David Tuller, DrPH Jonathan Sterne, a professor of medical statistics and epidemiology at Bristol University, is the corresponding author of Cochrane€™s revised €œrisk of bias€ tool, which BMJ published online on August 28th. Whatever the merits or defects of this revision, Professor Sterne€™s involvement as the first of more than two dozen authors has …

Trial By Error: Lead Author of Cochrane’s New Bias Guideline is LP Study Co-Author Read More »

By David Tuller, DrPH I have sent the following letter to Dr Fiona Godlee, editorial director of BMJ, about Archives of Disease in Childhood’s egregious decision to re-publish Bristol University’s Lightning Process trial with the original findings intact. Given the Bristol team’s flagrant methodological violations, the journal should have retracted the paper. Failing that, Archives …

Trial By Error: An Open Letter to Dr Godlee about BMJ’s Ethically Bankrupt Actions Read More »

By David Tuller, DrPH When I visited Melbourne in March of last year, I heard a lot about Dr Don Lewis, a local physician beloved by those with ME, or €œchronic fatigue,€ as Australian patients, scientists and clinicians routinely called the illness, to my dismay. At the time, Dr Lewis was transitioning out of his …

Trial By Error: My Interview with Melbourne’s Dr Don Lewis Read More »

By David Tuller, DrPH People who know little or nothing about the illness or cluster of illnesses variously called myalgic encephalomyelitis, chronic fatigue syndrome, CFS/ME, and ME/CFS can’t seem to stop writing stupid and ill-informed stories about it. And Professor Michael Sharpe seems to blame “Americans”–rather than his own disastrous research–for his current problems and …

Trial By Error: An Ill-Informed Article in The Guardian Read More »

By David Tuller, DrPH Some Australian members of the GET/CBT ideological brigades have published yet more nonsense and drivel about “graded exercise therapy” as a treatment for ME/CFS, or what they are still calling “chronic fatigue syndrome.” The article, simply called “Chronic fatigue syndrome: graded exercise therapy,” is in a peer-reviewed journal from a reputable …

Trial By Error: More GET Drivel from Australia Read More »

Most contemporary virologists use the term replication to indicate either the production of new virus particles or viral genomes. Because these are very different processes, during the preparation of the fourth edition of the textbook Principles of Virology, the authors decided to use the word reproduction to designate the production of new infectious virus particles, …

Viral reproduction and replication Read More »