The contamination of the rotavirus vaccine Rotarix with porcine circovirus 1 DNA was revealed by deep sequencing. The same technique was also used to demonstrate that oral poliovirus vaccine does not contain viruses that can cause poliomyelitis. The oral poliovirus vaccine strains developed by Albert Sabin (pictured) were licensed in the United States in 1962, …
Xenotropic murine leukemia virus related virus (XMRV) has been implicated in prostate cancer and chronic fatigue syndrome (CFS). Because XMRV is a retrovirus, it might be susceptible to antiviral drugs that are licensed for the treatment of AIDS. AZT (azidothymidine) was previously found to block XMRV replication. A screen of forty-five compounds reveals that XMRV …
Download: .wmv (343 MB) | .mp4 (94 MB) Visit the virology W3310 home page for a complete list of course resources.
Hosts: Vincent Racaniello and Stephen Goff Vincent speaks with Stephen Goff about the origin of the retrovirus XMRV and its association with prostate cancer and chronic fatigue syndrome. This episode is sponsored by Data Robotics Inc. Use the promotion code TWIVPOD to receive $75-$500 off a Drobo. Win a free Drobo S! Contest rules here. …
The recent discovery of contaminating porcine circovirus 1 DNA in Rotarix underscores the power of deep sequencing to ensure the purity of viral vaccines. The price of deep sequencing is now low enough that it is possible to use this technology to examine not just viral vaccines, but any biological product produced in mammalian cells …
At the Spring 2010 meeting of the Society for General Microbiology In Edinburgh I spoke about ‘Social Media in Microbiology Education and Research’. In my presentation I reviewed how I use blogging, podcasting, and other social media tools to teach the public about viruses. Below is a video recording of my presentation. Many thanks to …
