2015

Revisiting the PLoS One economics analysis of PACE

On October 23rd, virology blog published the third installment of David Tuller’s investigative report about the PACE study of treatments for ME/CFS. In the post, Dr. Tuller demonstrated that the key finding of an economic analysis of the PACE trial, published in PLoS One in 2012, was almost certainly false. The finding–that cognitive behavior therapy …

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Viruses help form biofilms

Bacteria frequently grow in communities called biofilms, which are aggregates of cells and polymers. An example of a biofilm is the dental plaque on your teeth. Biofilms are medically important as they can allow bacteria to persist in host tissues and on catheters, and confer increased resistance to antibiotics and dessication. Therefore understanding how biofilms form is …

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A request for data from the PACE trial

Mr. Paul Smallcombe Records & Information Compliance Manager Queen Mary University of London Mile End Road London E1 4NS Dear Mr Smallcombe: The PACE study of treatments for ME/CFS has been the source of much controversy since the first results were published in The Lancet in 2011. Patients have repeatedly raised objections to the study’s methodology and …

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