Virology
A Live-Attenuated Herpes Simplex Virus Vaccine Candidate
By Gertrud U. Rey
By Gertrud U. Rey There is currently no vaccine to prevent infection with herpes simplex virus type 1 or type 2 (HSV-1 or HSV-2). Infection with either of these viruses results in life-long viral latency. Sporadic reactivation and viral shedding may lead to painful oral and genital disease and an ...
TWiV 494: Ebola Makona is the opposite of hakuna matata
By Vincent Racaniello
Vincent, Kathy, and Alan review the ongoing outbreak of Ebola virus in the Democratic Republic of the Congo, and the finding that mutations identified in the 2015 West African epidemic do not alter pathogenesis in animals. <span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"></span><span data-mce-type="bookmark" style="display: inline-block; ...
TWiEVO 31: Virus archaeology, or when the human genome is the junk
By Vincent Racaniello
Nels and Vincent present ancient hepatitis B virus genome sequences from Bronze Age to Medieval period human remains. <span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"></span><span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"></span>&lt;span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"&gt;&lt;/span&gt;&lt;span data-mce-type="bookmark" ...
Humpback whale respiratory virome
By Vincent Racaniello
How difficult would it be to study the virome of living whales? You might think that sampling would be the hard part, but not if you used a drone. A drone was used to collect the breath ('blow') from 19 humpback whales near Sydney, Australia. The video below show how ...
TWiV 493: Condit is on drugs and norovirus is lit
By Vincent Racaniello
The TWiVerati discuss the FDA Advisory Committee deliberation on the anti-poxvirus drug tecovirimat, and immune cells in gut-associated lymphoid tissue as the major target during acute murine norovirus infection. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler <span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"></span><span data-mce-type="bookmark" ...