Of all the potential uses for genome editing via CRISPR/Cas9, perhaps the most exciting involves introducing therapeutic changes into human pluripotent stem cells (hPSCs) which can then be differentiated into many different cell types. A serious obstacle to such engineering is the finding that the tumor suppressor p53 inhibits CRISPR/Cas9 ...

https://youtu.be/wzTNzYmYG_U The entire TWiV team visits The University of Texas in Austin to record episode #500 with guests Jinny Suh, Jason McLellan, and Jon Huibregtse. <span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"></span>&lt;span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"&gt;&lt;/span&gt;&amp;lt;span data-mce-type="bookmark" style="display: inline-block; width: ...

Child in Papua New Guinea receiving OPV. Credit: WHO Last week we discussed the case of polio in Venezuela that turned out not to be polio. Unfortunately the same cannot be concluded about a bona fide case of polio in Papua New Guinea. Surveillance for acute flaccid paralysis (AFP) revealed ...

Vincent and Alan travel to the Canadian Society for Virology meeting in Halifax, Nova Scotia to speak with Nathalie and Craig about their vision for the society, and with Kate and Ryan about their careers and their research. <span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"></span>&lt;span data-mce-type="bookmark" ...

AFP surveillance in Pakistan. Image credit. In early June it was widely reported that the first case of poliomyelitis in 30 years had been identified in Venezuela (see this Tech Times report as an example). Fortunately these reports were incorrect, and Venezuela remains free of polio. Let€™s unpack exactly what ...