Virology

A lytic bacterium that behaves like a virus

Proposed C. destructans life cycle. Host mitchondria is brown. Image credit. What do you call a small bacterium that acts like a virus, infecting and lysing eukaryotic cells? Chromulinavvorax destructans, of course! As part of a study to identify pathogens that infect protist zooplankton, particles smaller than 0.8 microns were ...

TWiV 505: Rosebola

The TWiV hosts review persistence of Ebola virus after the end of the Liberian outbreak, and the potential role of two herpesviruses in the pathogenesis of Alzheimer's disease. <span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"></span>&lt;span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"&gt;&lt;/span&gt;&amp;lt;span data-mce-type="bookmark" ...

Herpesviruses and Alzheimer’s Disease

Roseola. Image credit. Risk factors for the chronic neurodegenerative condition known as Alzheimer's disease (AD) include many cellular genes and pathogenic microbes. Nucleic acids of two ubiquitous human herpesviruses, HHV-6A and HHV-7, have been found at higher levels in AD brains compared with healthy controls, and appear to regulate genes ...

TWiV 504: Flying foxes and barking pigs

The TWiVerinos discuss Nipah virus and the recent outbreak in India, and the first cast of polio in Papua New Guinea in 18 years. <span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"></span>&lt;span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"&gt;&lt;/span&gt;&amp;lt;span data-mce-type="bookmark" style="display: inline-block; width: 0px; ...

An inordinate fondness for viruses

I sat in the green room, 15 minutes before the start of the event, more nervous than I had been for a presentation in recent years. The occasion was the keynote address, which I was about to present before 1500 attendees at the 2018 annual meeting of the American Society ...
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