Virology
TWiV 520: This old mouse
By Vincent Racaniello
The TWiVidae review universal influenza vaccines that are in clinical trials, and discovery of an atypical parvovirus that causes chronic kidney disease in middle aged, immunocompromised laboratory mice. <span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"></span> Click arrow to play Download TWiV 520 (70 MB .mp3, 116 min) Subscribe ...
Leaving Koch behind
By Vincent Racaniello
For the past 40 years, certain laboratory mice in Australia and the US have been unexpectedly dying in middle age, but the cause has remained elusive. A novel member of the parvovirus family appears to be the culprit. These unexpected deaths of laboratory mice are caused by kidney disease, as ...
TWiV 519: Fishing for viruses in senile
By Vincent Racaniello
The TWiVomers review a potential role for herpes simplex virus type 1 as a cause of Alzheimer's Disease, including the finding that amyloid-beta acts as an antiviral by enveloping virus particles.  Click arrow to play Download TWiV 519 (58 MB .mp3, 96 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at ...
Herpes simplex virus and Alzheimer€™s disease
By Vincent Racaniello
Alois Alzheimer was the first to propose that an infection might play a role in the disease named after him. Herpes simplex virus type 1 (HSV-1) has been most frequently linked to Alzheimer€™s Disease (AD), and a clinical trial is in progress to determine if antivirals ameliorate its development. What ...
TWiV 518: Hershey’s viruses
By Vincent Racaniello
https://youtu.be/z63x9uSL7L0 Vincent travels to Penn State College of Medicine in Hershey, PA to speak with Nick Buchkovich and Leslie Parent about their careers and their work on human cytomegalovirus and retroviruses. <span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"></span> Click arrow to play Download TWiV 518 (53 MB .mp3, ...