https://youtu.be/z63x9uSL7L0 Vincent travels to Penn State College of Medicine in Hershey, PA to speak with Nick Buchkovich and Leslie Parent about their careers and their work on human cytomegalovirus and retroviruses. <span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"></span> Click arrow to play Download TWiV 518 (53 MB .mp3, ...

Tobacco mosaic virus-infected tobacco leaf. Image credit: Principles of Virology, 4th Edition, ASM Press. By Gertrud U. Rey Post-transcriptional gene silencing (PTGS) is an RNA regulation pathway in eukaryotes that depends on the presence of double stranded RNA (dsRNA) in the cytoplasm of cells. As stated by Nels Elde in ...

Brianne and Vincent tackle two studies that utilize infectious viruses to examine zoonotic potential of Bombali virus, a new ebolavirus from an insectivorous species in Sierra Leone, and a human mumps-like virus from an African flying fox in DRC.  Click arrow to play Download TWiV 517 (48 MB .mp3, 79 min) ...

A new drug has been approved by the US Food and Drug Administration for the treatment of influenza. Called Xofluza (baloxavir carboxyl), it is the first influenza drug approved in 20 years with a new mechanism of action. How does Xofluza work? Influenza virus particles contain (-) RNAs, which means ...

Lonya and Jeremy take the TWiV team beTWIXt primate immunodeficiency virus proteins Vpx and Vpr and how they counteract transcriptional repression of proviruses by the HUSH complex. <span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"></span>&lt;span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"&gt;&lt;/span&gt;&amp;lt;span data-mce-type="bookmark" style="display: inline-block; ...