Virology

Viral infections of the enteric nervous system and intestinal dysmotility

Intestinal dysmotility disorders such as irritable bowel syndrome affect 10-30% of humans in Western countries. Some of these diseases appear to correlate with viral infection. Inoculation of mice with neurotropic flaviviruses leads to injury and death of enteric neurons, inflammation, intestinal dilation and retarded bowel transit, providing a model for ...

TWiV 526: In the beginning there was pol

The TWiV hosts discuss the distribution of prions in the eyes of patients with sporadic Creutzfeldt-Jacob disease, and the origins and evolution of RNA viruses. <span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"></span>&lt;span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"&gt;&lt;/span&gt;&amp;lt;span data-mce-type="bookmark" style="display: inline-block; width: ...

These Bacteria are Bugged

By Gertrud U. Rey Quorum sensing is a form of cell to cell communication in bacteria in which individual cells coordinate their behavior based on population density. In human terms, the word "quorum" means "the minimum number of people required to conduct business." During quorum sensing, bacteria produce and release ...

TWiV Special: Vaccines Did Not Cause Rachel’s Autism

Vaccine scientist, pediatrician, and autism dad Peter Hotez talks about his new book, Vaccines Did Not Cause Rachel's Autism. <span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"></span>&lt;span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"&gt;&lt;/span&gt;&amp;lt;span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"&amp;gt;&amp;lt;/span&amp;gt;&amp;amp;lt;span ...

An inborn error of innate immunity leading to severe rhinovirus infections

When a human population is exposed to a pathogenic virus, the outcomes among individuals may include asymptomatic, mild, severe, or no infection. Multiple parameters control these responses, including the amount of virus taken up, the age of the host, general health status, nutrition, and more. With the advent of whole ...
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