Virology
TWiV 536: A flock of seagulls, a herd of seals
By Vincent Racaniello
https://youtu.be/Bipgn9Yq8yg Vincent and Alan travel to Tufts Veterinary School where they meet up with members of the Runstadler lab to talk about their work on influenza virus circulation in water birds and seals. Click arrow to play Download TWiV 536 (54 MB .mp3, 96 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes ...
Ribosomal proteins encoded in viral genomes
By Vincent Racaniello
When I first entered the field of virology, in the 1970s, the definition of virus included the then-correct observation that no viral genome encoded any part of the translational apparatus. This dictum was shattered by the discovery of giant viruses which were found to encode tRNAs, aminoacyl tRNA syntheses, and ...
TWiV 535: Miles to go before I leak
By Vincent Racaniello
The TWiV team discuss the use of quantum dots to study uncoating of influenza virus in real time, and induction of endothelial dysfunction by flavivirus NS1 proteins in a tissue-specific manner. Click arrow to play Download TWiV 535 (58 MB .mp3, 96 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv
A portal for RNA exit
By Vincent Racaniello
Top view of calicivirus portal. VP1 is green, VP2 is red. Virus particles are metastable: they must be highly stable, to protect the nucleic acid while traveling from host to host or cell to cell, and then come apart to liberate the genome into the cell. New insight into this ...
TWiV 534: Portal to the METTL
By Vincent Racaniello
The TWiV crew reveal a unique portal on the calcivirus capsid formed upon receptor engagement, and the regulation of interferon responses in virus-infected cells by methylation of mRNA. Click arrow to play Download TWiV 534 (57 MB .mp3, 95 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv
