Virology

Rabbits and viruses: An iconic example of natural selection

When viruses are introduced into a new population, selection pressures can lead to evolution of both pathogen and host. The pathogen must adapt to a new host, while the latter can become resistant to infection, leading to an arms race. An archetypal example of such host-pathogen evolution is illustrated by ...

TWiV 539: Multitudes contain me

The TWiV hosts present two potentially seminal papers, on long-distance chemoattraction of a host by a chlorovirus, and replication of a nanovirus across multiple cells in a plant. Click arrow to play Download TWiV 539 (62 MB .mp3, 102 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv

The London Patient

by Gertrud U. Rey Timothy Ray Brown, also known as the Berlin patient (reviewed in a previous post), was the only person ever to be cured of HIV/AIDS. Until last week. In a report published in the journal Nature, a group of investigators announced the cure of a second HIV-positive patient ...

TWiV 538: An Iowa caucus of viruses

https://youtu.be/srQZPmK5n5c TWiV travels to the University of Iowa to speak with Wendy Maury and Stanley Perlman about their research on Ebolavirus entry and coronavirus pathogenesis. Click arrow to play Download TWiV 538 (37 MB .mp3, 62 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv

A fatal attraction

Viruses have no intrinsic means of locomotion, but because of their small size their movement can be driven by Brownian motion. Propagation of viruses is dependent on essentially random encounters with potential hosts and host cells. An exception appears to be chloroviruses, which can attract their host from a distance. ...
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