Virology

Michael Rossmann, 88

https://youtu.be/LJDkocKSQv8 Michael Rossmann, a leader in the use of X-ray crystallography and cry-electron microscopy to solve the structure of viruses, died on 14 May 2019 at the age of 88. I met Michael many times but had the good fortune to interview him during the preparation of the fourth edition ...

TWiV 547: Upstate virology

https://youtu.be/NljaZLYtSvg Vincent travels to the University at Albany to speak with Cara, Rachel, and Alex about their careers and their work on stress granules, epitranscriptomics, and arboviruses. Click arrow to play Download TWiV 547 (58 MB .mp3, 96 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv

A risky vaccine

by Gertrud U. Rey Dengue fever, caused by dengue virus (DENV), is of substantial public health significance in the tropics, where the virus is spread by Aedes mosquitoes. Last week the FDA announced its approval of a first vaccine for the prevention of dengue disease in endemic areas. The vaccine approved by ...

Hepatitis delta-like virus in birds and snakes

Hepatitis D virus is a unique human pathogen. With a circular, negative stranded RNA genome of ~1700 nucleotides, it is the smallest known human virus. Formation of the HDV particle depends on co-infection of cells with a helper virus, hepatitis B virus. Once thought to be specific for humans, related ...

Complementing neutralization of viruses by antibodies

Viral infection of vertebrates leads to the production of antibodies, and some of these can block virus infection by a process that is called neutralization. Antibodies can neutralize viral infectivity in a number of ways: they may impair virus entry into cells, and even cause degradation of the capsid in ...
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