Each year I inform the students in my Columbia University virology course that all known DNA polymerases - viral or cellular - require a primer to initiate DNA synthesis (it€™s even stated in our textbook, Principles of Virology). This statement is no longer true, as shown by the discovery of ...

https://youtu.be/DQqKEhfGXNw At Retroviruses 2019 in Cold Spring Harbor, Vincent speaks with virologist Bryan Cullen about his work and his career, together with former associates Ann Skalka, Paul Bieniasz, and Michael Malim. Click arrow to play Download TWiV 551 (37 MB .mp3, 60 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV!

By Gertrud U. Rey Every year approximately 1800 high school students from more than 80 different countries gather at the Intel International Science and Engineering Fair (ISEF), where they display their independent research and compete for more than $5 million worth of prizes. Last month, I had the honor of serving ...

TWiV explains the use of a neuronal cell line to study herpes simplex virus latency and reactivation, and a strategy for creating vaccines that induce antibodies against specific epitopes. Click arrow to play Download TWiV 550 (64 MB .mp3, 105 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv

Influenza virus (left). HA is shown in blue. Right, HA molecule. Colored atoms illustrate variable epitopes on the HA head, and conserved epitopes on the HA stem. A method for making vaccines that induce antibodies against a specific epitope could be used to produce a universal influenza vaccine that would not ...