Virology
Neurotropism of enterovirus D68 is not a recently acquired property
By Vincent Racaniello
with Amy Rosenfeld Enterovirus D68 (EV-D68) was first isolated from children with respiratory disease in 1962. No outbreaks of infection were detected until the late summer and early fall of 2014, and then in 2016 and 2018. During these epidemics of respiratory disease, some children developed polio-like paralysis. We have ...
Wild poliovirus type 3 declared eradicated
By Vincent Racaniello
Today, on World Polio Day, wild poliovirus type 3 has been declared eradicated by a commission of the World Health Organization. The last case of type 3 poliomyelitis was recorded in 2012 in Nigeria. Because wild poliovirus type 2 was declared eradicated in 2015, now only wild poliovirus type 1 ...
TWiV 570: Aarhus viral
By Vincent Racaniello
At Aarhus University in Denmark, Vincent speaks with Trine Mogensen, Søren Paludan, Ole Søgaard, and Madalina Carter-Timofte about their careers and their work on sensing herpesviral DNA, immunodeficiencies that predispose to severe viral infections, and the path to a cure for HIV/AIDS. Click arrow to play Download TWiV 570 (61 MB .mp3, ...
Segmented filamentous bacteria block rotavirus infection
By Vincent Racaniello
Viruses and bacteria are both present at mucosal surfaces and it is not surprising that they interact in many ways. Sometimes members of the gut microbiome help viruses to infect cells, exemplified by poliovirus, reovirus, and mouse mammary tumor virus. The opposite also happens: segmented filamentous bacteria can prevent and ...
TWiV 569: Smolt’in iron
By Vincent Racaniello
The TWiV pro-vaxxers reveal viruses that infect endangered wild salmon, and how iron in host serum modulates dengue virus acquisition by mosquitoes. Click arrow to play Download TWiV 569 (67 MB .mp3, 110 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv