Virology
TWiV #18: Can a virus make you fat?
By Vincent Racaniello
On This Week in Virology #18, Vincent, Dick, and Alan discuss adenovirus type 36 and obesity, new influenza antiviral drugs, viral hemorrhagic septicemia virus of fish, and Ebola virus in pigs and pig farmers in the Phillipines. Click the arrow above to play, or right-click to download TWiV #18
Viruses and obesity?
By Vincent Racaniello
The past week brought an animated discussion triggered by an article in Obesity which reported the adipogenic effect of adenovirus type 36 infection in cultured cells. The press had a field day with headlines like 'Can a common cold virus really make you fat'?. Reactions on Twitter and blogs ranged ...
Innate sensors of DNA
By Vincent Racaniello
The innate immune system responds within minutes of infection to produce type I interferons and pro-inflammatory cytokines. Interferons induce the synthesis of cell proteins with antiviral activity, and also shape the adaptive immune response by priming T cells. Despite the discovery of interferons over 50 years ago, only recently have ...
New influenza antiviral drugs
By Vincent Racaniello
The success in treating AIDS with multiple combinations of three antiviral drugs is a model for the successful management of viral resistance. Can we expect that a deep arsenal of anti-influenza virus drugs will be developed? So far we have three antiviral drugs against influenza viruses. Most H3N2 strains are ...
John Updike, 1932-2009
By Vincent Racaniello
Here is my favorite poem about science. I found it stuck on the wall in my empty lab when I first came to Columbia in the fall of 1982. It is still tacked to my corkboard, yellowing and frayed. V.B. Nimble, V.B. Quick (inspired by V.B. Wigglesworth, F.R.S., Quick Professor ...
