Virology

TWiV #20: Hepatitis C virus

On This Week in Virology episode 20, Vincent, Dick, and Alan are joined by hepatitis C virus expert Matt Evans. They converse about TED, the Wakefield autism controversy, 99 rhinovirus sequences, Marburg in the USA, and hepatitis C virus. Click the arrow above to play, or right-click to download TWiV ...

Sensor face

While preparing a figure for a review article on innate sensing of RNA, I realized that the image was taking on facial features. I thought the readers of virology blog might be amused by the image that I created. Click on the thumbnail at left for a larger view. Now ...

Acute viral infections

An acute viral infection is characterized by rapid onset of disease, a relatively brief period of symptoms, and resolution within days. It is usually accompanied by early production of infectious virions and elimination of infection by the host immune system. Acute viral infections are typically observed with pathogens such as ...

Infectious DNA clones

The development of recombinant DNA methods by Cohen and Boyer in 1973, together with the discovery of reverse transcriptase by Temin and Baltimore in 1970, made it possible to introduce a mutation at any location in a viral genome. The essential reagent is an infectious DNA clone, a double-stranded DNA ...

Marburg virus travels to the US

The first US case of Marburg hemorrhagic fever was reported last month in Colorado. Will there be more? The patient had traveled to Uganda in December 2007 and visited a python cave, which houses thousands of bats - some of which might be reservoirs for Marburg virus. Two weeks after ...
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