Virology
TWiV #27: Leaving latency
By Vincent Racaniello
On episode #27 of the podcast "This Week in Virology", Vincent, Dick, Alan, and Saul Silverstein revisit an ebolavirus needlestick accident, and discuss the role of TLR3 in formation of Negri bodies, a New England college closed by norovirus gastroenteritis, hand, foot, and mouth disease outbreak in China, and the ...
How herpes simplex virus exits latency
By Vincent Racaniello
Many of us have experienced herpesvirus reactivation from latency. Suddenly a sore erupts on the lip, festers for a week, then subsides. Years later, for no apparent reason, it happens again. Did you ever wonder what causes these recurrent blisters? Herpes simplex viruses are associated with latent infections, a type ...
Hand, foot, and mouth disease outbreak in China
By Vincent Racaniello
An outbreak of hand, foot, and mouth disease in China has lead to 41,000 infections and 18 deaths this year. What is this disease and what causes it? Hand, foot, and mouth disease (HFMD) is a rather common viral infection of children. There were 80,000 recorded cases of the disease ...
Negri bodies and rabies
By Vincent Racaniello
Viral replication frequently leads to the accumulation of intracellular masses of virions or unassembled viral components in the cytoplasm or nucleus of the cell. These inclusion bodies often bear the name of the individual who discovered them - such as Guarnieri bodies in the cytoplasm of poxvirus infected cells, intranuclear ...
Futures in Biotech on influenza
By Vincent Racaniello
I joined host Dr. Marc Pelletier on the TWiT podcast 'Futures in Biotech' to interview influenza virologist Dr. Peter Palese, professor and chair of microbiology at the Mount Sinai School of Medicine in New York. We talk about influenza and why Dr. Palese revived a virus that killed 50 million people. Download Futures ...