Virology
Viruses and the respiratory tract
By Vincent Racaniello
Now that we have a rudimentary understanding of influenza virus replication, we can begin to consider how the virus causes disease - a field of study called viral pathogenesis. The first step in this process is virus entry into the body. The human body is covered with skin, which has ...
Why don’t DNA based organisms discard error repair?
By Vincent Racaniello
The recent series of posts on polymerase error rates and viral evolution has elicited many excellent and thought provoking comments from readers of virology blog. Here is one that I had not thought of before, and which I'll use on an exam in my virology course: Here's a tough question. ...
Assembly of influenza virus
By Vincent Racaniello
Our discussion of influenza virus replication has so far brought us to the stage of viral RNA synthesis. Last time we discussed the formation of viral RNAs, an event which takes place in the cell nucleus. Now we'll consider how these RNAs participate in the assembly of new infectious viral ...
Co-circulation of three human influenza A subtypes
By Vincent Racaniello
Although the new influenza H1N1 strain has been receiving a great deal of attention, apparently last season's H1N1 and H3N2 strains continue to circulate, at least in the United States. FluView, the weekly surveillance report from the CDC, indicates that during weeks 17 and 18, seasonal influenza A (H1), A ...
TWiV 32: Influenza in silico
By Vincent Racaniello
On episode #32 of the podcast This Week in Virology, Vincent, Alan, and Raul Rabadan converse about polio survivors in iron lungs, bocavirus, structure of mimivirus, and genome sequence analysis of influenza H1N1 viruses. [powerpress url="http://traffic.libsyn.com/twiv/TWiV032.mp3"] Click the arrow above to play, or right-click to download TWiV #32 or subscribe ...
