Virology
Lujo virus, a new hemorrhagic fever virus from Southern Africa
By Vincent Racaniello
A new member of the arenavirus family, Lujo virus, has been identified in patients who died during an outbreak of hemorrhagic fever in late 2008. Sequence analysis reveals that Lujo is a new arenavirus, genetically distinct from other members of the family which includes Lassa virus. A patient with unexplained ...
Influenza microneutralization assay
By Vincent Racaniello
The microneutralization assay is another technique used by the Centers for Disease Control and Prevention to determine that some adults have serum cross-reactive antibodies to the new influenza H1N1 virus. Let's explore how this assay works. Viral replication is often studied in the laboratory by infecting cells that are grown ...
Influenza hemagglutination inhibition assay
By Vincent Racaniello
Centers for Disease Control and Prevention have determined that some adults have serum cross-reactive antibodies to the new influenza H1N1 virus. One of the techniques used to reach this conclusion is the hemagglutination inhibition (HI) assay. How does this assay work? To understand the HI assay, we must discuss the ...
TWiV 33: Live in Philly video
By Vincent Racaniello
Thanks to Chris Condayan and Ray Ortega of the American Society for Microbiology for recording and editing TWiV live at the ASM General Meeting in Philadelphia, 19 May 2009.
US to redirect $1 billion to study adjuvant for influenza vaccine
By Vincent Racaniello
Health and Human Services (HHS) Secretary Kathleen Sebelius announced on Friday that she is allocating $1 billion in existing funds to purchase large quantities of vaccine against the novel H1N1 influenza strain, and to conduct clinical trials this summer to determine if an adjuvant can be used. If this money ...
