Virology

Adults have cross-reactive antibodies to A/California/04/2009 (H1N1)

Does previous exposure to influenza H1N1 viruses, either by infection or vaccination, provide any protection against infection with the new H1N1 influenza virus strains? The answer to this question might provide insight as to why over 60% of confirmed cases of influenza caused by the swine-like H1N1 viruses in the ...

Viruses and the respiratory tract

Now that we have a rudimentary understanding of influenza virus replication, we can begin to consider how the virus causes disease - a field of study called viral pathogenesis. The first step in this process is virus entry into the body. The human body is covered with skin, which has ...

Why don’t DNA based organisms discard error repair?

The recent series of posts on polymerase error rates and viral evolution has elicited many excellent and thought provoking comments from readers of virology blog. Here is one that I had not thought of before, and which I'll use on an exam in my virology course: Here's a tough question. ...

Assembly of influenza virus

Our discussion of influenza virus replication has so far brought us to the stage of viral RNA synthesis. Last time we discussed the formation of viral RNAs, an event which takes place in the cell nucleus. Now we'll consider how these RNAs participate in the assembly of new infectious viral ...

Co-circulation of three human influenza A subtypes

Although the new influenza H1N1 strain has been receiving a great deal of attention, apparently last season's H1N1 and H3N2 strains continue to circulate, at least in the United States. FluView, the weekly surveillance report from the CDC, indicates that during weeks 17 and 18, seasonal influenza A (H1), A ...
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