Virology

Pandemic quiz

The World Health Organization has declared that the world is now at the start of an influenza pandemic. WHO Director-General Dr. Margaret Chan said today: I have conferred with leading influenza experts, virologists, and public health officials. In line with procedures set out in the International Health Regulations, I have ...

The trajectory of evolution

Scientists and philosophers have long debated the trajectory of evolution. Some of the questions they consider include: is there a predictable direction for evolution, and if there is, what is the pathway? Are there evolutionary dead ends? Viruses are excellent subjects for the study of evolution: they have short generation ...

Virulence: A positive or negative trait for evolution?

With just 141 confirmed deaths so far, an interesting question is whether the 2009 H1N1 influenza virus could mutate into something more lethal ("How a Mild Virus Might Turn Vicious"). Of course it could - but is it beneficial for the virus? A fundamental principle of viral evolution is that ...

Influenza virus in the toilet

While perusing the cleaning items at the supermarket last night, I spotted the words 'Kills Flu Virus' on a bottle of toilet bowl cleaner. Do toilets play a role in transmission of influenza? Influenza is an infection of the respiratory tract. The virus enters the tract in aerosols or by ...

Was the swine influenza threat underestimated?

Many virologists, including myself, believe that the threat of avian H5N1 influenza is not only overestimated, but also distracts from serious consideration of other potential pandemic strains. In early 2005 I wrote about this problem ("Should we worry about avian influenza?) and suggested that we should pay attention to H2N2 ...
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