Virology
Detecting viruses: the plaque assay
By Vincent Racaniello
One of the most important procedures in virology is measuring the virus titer - the concentration of viruses in a sample. A widely used approach for determining the quantity of infectious virus is the plaque assay. This technique was first developed to calculate the titers of bacteriophage stocks. Renato Dulbecco ...
TWiV 39: Virus structure
By Vincent Racaniello
Hosts: Vincent Racaniello and Dick Despommier On episode #39 of the podcast "This Week in Virology", Vincent and Dick discuss virus structure and answer listener questions. [powerpress url="http://traffic.libsyn.com/twiv/TWiV039.mp3"] Click the arrow above to play, or right-click to download TWiV #39 (37 MB .mp3, 53 minutes) Subscribe to TWiV in iTunes, by ...
Adaptive immune defenses
By Vincent Racaniello
The immune response to viral infection comprises innate and adaptive defenses. The innate response, which we have discussed previously, functions continuously in a normal host without exposure to any virus. Most viral infections are controlled by the innate immune system. However, if viral replication outpaces innate defenses, the adaptive response ...
The inflammatory response
By Vincent Racaniello
During the earliest stages of a virus infection, cytokines are produced when innate immune defenses are activated. The rapid release of cytokines at the site of infection initiates new responses with far-reaching consequences that include inflammation. One of the earliest cytokines produced is tumor necrosis factor alpha (TNF-α), which is ...
Many adults cannot name a scientist
By Vincent Racaniello
USA Today's Snapshot for 29 June was a survey in which 1000 adults were asked to name a famous scientist. Here are the results: 47% named Albert Einstein 23% could not name anyone 6% named Marie Curie 4% named Louis Pasteur 4% named Thomas Edison The survey was conducted by ...
