Antibodies produced by infection with a virus, or after immunization with viral vaccines, are effective at preventing viral disease. However humans and higher primates contain "natural antibodies" which are present in serum before viral infection. Natural antibodies can activate the classical complement pathway leading to lysis of enveloped virus particles ...

Hosts: Vincent Racaniello and Scott Hammer, MD On episode #52 of the podcast "This Week in Virology", Vincent and Dr. Scott Hammer talk about different types of AIDS vaccines and how they are tested in clinical trials. [powerpress url="http://traffic.libsyn.com/twiv/TWiV052.mp3"] Click the arrow above to play, or right-click to download TWiV ...

Here at Columbia University Medical Center, all employees and students may receive, at no charge, influenza vaccine every year. I just went to the lobby of the Milstein Hospital, showed my ID, and received the seasonal influenza vaccine. Here is the proof: As I've written before, vaccine records provide interesting ...

The classical complement pathway begins when the initiator protein C1q binds directly to the surface of a pathogen, or to an antibody that is bound to a microbe. There is a binding site for C1q on the Fc portion of antibody molecules. C1q can also recognize molecular patterns characteristic of pathogens, much like ...

During the more than 30 years that I have studied viruses, I have had many opportunities to speak with journalists of different kinds. For the most part, the print journalists have done a good job at accurately presenting the science, but I cannot say the same for my experience on ...