Use of the rotavirus vaccine Rotarix in the US has been temporarily suspended because the vaccine was found to be contaminated with porcine circovirus 1 DNA. The discovery was made in the laboratory of Dr. Eric Delwart, who has provided insight into what was found in Rotarix, and why he ...

Hosts: Vincent Racaniello, Alan Dove, and Matthew Frieman Vincent, Alan, and Matt review contamination of Rotarix with circovirus DNA, antigenic similarity between 1918 and 2009 H1N1 influenza, a collection of rabies reports, and chicken pox mistaken for smallpox in Uganda. This episode is sponsored by Data Robotics Inc. Use the ...

The US Food and Drug Administration does not want Rotarix, the rotavirus vaccine, to be used because it contains porcine circovirus 1 DNA. If complete copies of the circovirus genome were present, would they constitute a potential threat to recipients? Put another way, is circovirus DNA infectious? Here is the ...

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