Virology

Derek Lowe on how science gets done

Organic chemist Derek Lowe writes about XMRV at his blog, In the Pipeline: ...this isn't looking good at all. It's pretty typical, though, of how things are out at the frontiers in this business. There are always more variables than you think, and more reasons to be wrong than you've ...

TWiV 115: Color me infected

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Marc Pelletier On episode #115 of the podcast This Week in Virology, Vincent, Alan, Rich and Marc discuss the finding that a limited number of incoming herpesviral genomes can replicate and express in a cell, and controlling viral replication in Aedes aegypti with a Wolbachia ...

Derek Smith on antigenic cartography

Derek Smith, Professor of Infectious Disease Informatics, University of Cambridge, U.K., has developed a method for visualizing antigenic evolution by creating two-dimensional maps in a process called antigenic cartography. These maps are made with data that provide information on the antigenic properties of the pathogen. In the case of influenza ...

Retroviral integration and the XMRV provirus

A strong argument that the novel human retrovirus XMRV is not a laboratory contaminant is the finding that viral DNA is integrated in chromosomal DNA of prostate tumors. Why does this result constitute such strong proof of viral infection? Establishment of an integrated copy of the viral genome - the ...

TWiV 114: Ten out of ’10

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit On episode #114 of the podcast This Week in Virology, Vincent, Alan, and Rich revisit ten compelling virology stories of 2010. [powerpress url="http://traffic.libsyn.com/twiv/TWiV114.mp3"] Click the arrow above to play, or right-click to download TWiV #114 (64 MB .mp3, 88 minutes). Subscribe to TWiV (free) in iTunes ...
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