The TWiVaniellos discuss a thermostable poliovirus empty capsid vaccine, and two cell genes that act as a switch between entry and clearance of picornavirus infection. You can find TWiV #425 at microbe.tv/twiv, or listen below. [powerpress url="http://traffic.libsyn.com/twiv/TWiV425.mp3"] Click arrow to play Download TWiV 425 (65 MB .mp3, 107 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV!

A unique feature of eukaryotic cells, which distinguishes them from bacteria, is the presence of a membrane-bound nucleus that contains the chromosomal DNA (illustrated; image credit). Surprisingly, a nucleus-like structure that forms during viral infection of bacteria is the site of viral DNA replication (link to paper). During infection of Pseudomonas bacteria ...

I spoke with Jonna Mazet, PhD, UC Davis School of Veterinary Medicine, about emerging pathogen surveillance and public health. Dr. Mazet is the Principal Investigator and Global Director of the novel viral emergence early warning project, PREDICT, that has been developed with the US Agency for International Development's (USAID) Emerging Pandemic ...

Trudy joins the the TWiVlords to discuss new tests for detecting prions in the blood, and evidence showing that foamy retroviruses originated in the seas with their jawed vertebrate hosts at least 450 million years ago. You can find TWiV #424 at microbe.tv/twiv, or listen below. [powerpress url="http://traffic.libsyn.com/twiv/TWiV424.mp3"] Click arrow to ...

I spoke with virologist Ian Goodfellow, whose laboratory works on noroviruses, about why he went to Sierra Leone to establish an Ebolavirus diagnostic and sequencing laboratory. The obstacles he encountered were considerable, but the results were very useful. Recorded at the Emerging Infectious Diseases A to Z (EIDA2Z) conference hosted by the National ...