Virology
TWiV 458: Saliva of the fittest
By Vincent Racaniello
The TWiVians present an imported case of yellow fever in New York City, and explain how a dengue virus subgenomic RNA disrupts immunity in mosquito salivary glands to increase virus replication. Click arrow to play Download TWiV 458 (72 MB .mp3, 119 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv.
Roger W. Hendrix, 74
By Vincent Racaniello
Virologist Roger W. Hendrix died on 15 August 2017. I only met Roger once, at the 2011 ASM meeting in New Orleans where we recorded an episode of This Week in Virology. The video of that episode is below, starting at my conversation with Roger at 30:34. Harmit Malik and ...
Thirty-five years later
By Vincent Racaniello
Thirty-five years ago this month, in September 1982, I arrived at Columbia University College of Physicians & Surgeons to open my virology laboratory. I brought with me an infectious DNA copy of the poliovirus RNA genome, the first of its kind, and a lot of enthusiasm. Over the years we ...
TWiV 457: The Red Queen meets the White Rabbit
By Vincent Racaniello
Brianne returns to the TWiV Gang to discuss the distribution of proteins on the influenza viral genome, and the evolution of myxoma virus that was released in Australia to control the rabbit population. Click arrow to play Download TWiV 457 (74 MB .mp3, 123 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV! Show notes at ...
A plasmid on the road to becoming a virus
By Vincent Racaniello
Plasmids have been discovered that can move from cell to cell within membrane vesicles in a species of Archaea (link to paper). They provide clues about the origin of virus particles. Electron microscope analysis of the culture medium from Halobrum lacusprofundi R1S1, an Archaeal strain from Antarctica, revealed spherical particles ...