Virology
A problem with dengue virus vaccine
By Vincent Racaniello
A dengue virus vaccine was recently developed not only to prevent first infections, but to avoid severe disease that may occur upon second and third infections. This consequence, called antibody dependent enhancement (ADE), now appears to be caused by the vaccine itself. Primary dengue virus infection may lead to a ...
TWiV 470: Just a passing phage
By Vincent Racaniello
The TWiV ninjas reveal that bacteriophage particles rapidly move across monolayers of eukaryotic cells from different tissues. <span data-mce-type="bookmark" class="mce_SELRES_start"></span><span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"></span>&lt;span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"&gt;&lt;/span&gt; Click arrow to play Download TWiV 470 (71 MB .mp3, 117 min) ...
How a toupee compromised influenza vaccine
By Vincent Racaniello
The influenza virus vaccine is frequently updated to ensure that it protects against infection with circulating virus strains. In some years the vaccine matches the circulating strains, but in others, there is a mismatch. The result is that the vaccine is less effective at protecting from infection. During the 2014-15 ...
TWiV 469: Mycovirus stuffed potatoes
By Vincent Racaniello
The TWiV hosts discuss a plant virus that infects a fungus, and whether you need to work insane hours to succeed in science. <span data-mce-type="bookmark" class="mce_SELRES_start"></span><span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"></span> Click arrow to play Download TWiV 469 (66 MB .mp3, 108 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV! ...
Immune 2: Lymphocytes after dark
By Vincent Racaniello
Cindy, Steph, and Vincent reveal that lymphocyte trafficking through lymph nodes and lymph is circadian - it is dependent on the time of day. <span data-mce-type="bookmark" class="mce_SELRES_start"></span> Click arrow to play Download Immune 2 (53 MB .mp3, 87 min) Subscribe (free): iTunes, RSS, email Become a patron of Immune! Show notes at microbe.tv/immune
