by Gertrud U. Rey Lithium-ion batteries produce power when lithium ions flow from a negative electrode to a positive electrode through an electrolyte medium. The positive electrode is usually composed of a lithium compound and the negative electrode is typically graphite (crystalline carbon).
The TWiV team returns this week to SARS-CoV-2019 coverage to review the latest epi curves, the fatality rate, furin cleavage site and receptor binding domain in the spike glycoprotein, related CoV recovered from pangolins, evidence that the virus did not escape from a laboratory, and many more questions sent in by listeners. Click arrow to …
TWiV 588: Coronavirus update – Save the pangolin! Read More »
A coronavirus related to SARS-CoV-2 has been isolated from Malayan pangolins illegally imported into Guangdong province. It is not the precursor of SARS-CoV-2, but comparison of viral genome sequences provides further evidence that the virus currently infecting humans was not produced in a laboratory. There are two important sequences in the viral spike glycoprotein (pictured) …
Pangolins and the origin of SARS-CoV-2 coronavirus Read More »
The spike glycoprotein of the newly emerged SARS-CoV-2 contains a potential cleavage site for furin proteases. This observation has implications for the zoonotic origin of the virus and its epidemic spread in China. The membrane of coronaviruses harbors a trimeric transmembrane spike (S) glycoprotein (pictured) which is essential for entry of virus particles into the …
Furin cleavage site in the SARS-CoV-2 coronavirus glycoprotein Read More »
In this week’s coverage of the coronavirus epidemic, the TWiV team discusses the fatality rate, China’s initial reaction to the outbreak, conspiracy theories, how long the virus remains infectious on surfaces, and evidence for virus in the intestinal tract. Click arrow to play Download TWiV 586 (72 MB .mp3, 119 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! …
by Gertrud U. Rey Herpes simplex viruses establish lifelong persistent infection in sensory neurons of infected individuals, a phenomenon called latency. Latent viral genomes are “dormant” but can sporadically reactivate and begin replicating in a phase called lytic replication, which is often accompanied by shedding of virus particles and the appearance of painful lesions. There …
