After my lecture on influenza pathogenesis and evolution at the Northeast Laboratory Conference 2010 in Portland, Maine, I was asked if it is necessary to receive the influenza vaccine every year. This question was precipitated by my statement that the 2010-11 trivalent influenza vaccine contains the same swine-origin H1N1 strain as last year€™s monovalent vaccine. …
Hosts: Vincent Racaniello, Alan Dove, and LJ Tan On Episode 103 of the podcast This Week in Virology, Vincent and Alan discuss influenza vaccines with LJ Tan of the American Medical Association. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV103.mp3″] Click the arrow above to play, or right-click to download TWiV #103 (56 MB .mp3, 77 minutes) Subscribe to TWiV (free) in …
The need to re-formulate the influenza virus vaccine in response to viral antigenic drift and shift makes for complex logistics of vaccine production and administration. Surveillance programs must be conducted each year to identify strains that are likely to predominate and cause disease. Wouldn€™t it be simpler if a single vaccine could be developed that …
Hosts: Vincent Racaniello, Andrew Baker, Karl-Klaus Conzelmann, Peter Palese, and Katharina Eisenächer Episode #102 of the podcast This Week in Virology is a conversation about the RNA sensor RIG-I, adenovirus gene therapy, a universal influenza vaccine, and rabies virus, recorded in Munich, Germany at the SFB455 symposium ‘Viral offense and immune defense€™. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV102.mp3″] Click the arrow above to …
Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Eric F. Donaldson On episode #90 of the podcast This Week in Virology, Vincent, Alan, Rich and Eric discuss identification of viruses in Northeastern American bats, vaccinia virus infection after sexual contact with a military vaccinee, and identification of a new flavivirus from an Old World bat in …
A serious shortcoming of current influenza virus vaccines is the need to reformulate them every year or two as the virus undergoes antigenic drift. Many virologists have been captivated by the idea of a more universal vaccine that would endure longer, perhaps a decade or more. The identification of a conserved domain in the stalk …
