The polio eradication and endgame strategic plan announced by the World Health Organization in 2014 includes at least one dose of inactivated poliovirus vaccine (IPV). Since 1988, when WHO announced the polio eradication plan, it had relied exclusively on the use of oral poliovirus vaccine (OPV). The rationale for including a dose of IPV was …
An unexpected benefit of inactivated poliovirus vaccine Read More »
On episode #318 of the science show This Week in Virology, the TWiV gang reviews ten fascinating, compelling, and riveting virology stories from 2014. You can find TWiV #318 at www.microbe.tv/twiv.
I have received many questions about whether immunizing with Reston virus could protect against infection with Ebola virus. Usually the question comes together with the statement ‘because Reston virus does not cause disease in humans’. I can think of two reasons why a Reston virus vaccine is not a good idea. There have been very few …
Could Reston virus be a vaccine for Ebola virus? Read More »
The World Health Organization held a conference to assess the status of testing and eventual licensing of two candidate Ebola virus vaccines. The agenda and list of participants and the final report are available. I was interested in the following list of key expected milestones: October 2014: Mechanisms for evaluating and sharing data in real time must be …
WHO assessment of experimental Ebola virus vaccines Read More »
I cannot pass up the opportunity to point out this wonderful quote by Ginia Ballafante in her NY Times piece, Fear of Vaccines Goes Viral. The article starts by noting an article on plummeting vaccination rates in Los Angeles: The piece had the virtue of offering New Yorkers yet another opportunity to feel smugly superior to …
The cover of this week’s issue of Businessweek declares that ‘Ebola is coming’ in letters colored like blood, with the subtitle ‘The US had a chance to stop the virus in its tracks. It missed’. Although the article presents a good analysis of the hurdles in developing antibody therapy for Ebola virus infection, the cover …
Could the Ebola virus epidemic have been prevented? Read More »
