by Gertrud U. Rey As discussed in my previous post, we first became aware of human immunodeficiency virus (HIV) in the early 1980s. However, when did the virus actually emerge in humans, and where did it come from? There are two strains of HIV – HIV-1 and HIV-2. The vast majority of infections are caused …
Lonya and Jeremy take the TWiV team beTWIXt primate immunodeficiency virus proteins Vpx and Vpr and how they counteract transcriptional repression of proviruses by the HUSH complex. <span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span><span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span>&lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: …
TWiV 516: HUSH little virus, don’t you transcribe Read More »
Ned Landau joins the TWiV team to discuss restriction of HIV replication by SAMHD1, and a viral antagonist that can be used to produce a dendritic cell vaccine. <span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span><span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span><span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: …
Lemurs are primates found only on the island of Madagascar and a few small neighboring islands. Some of these animals have endogenous lentiviruses in their genomes. How did these viruses infect the isolated lemurs?
Jeremy joins the TWiVeroids to tell the amazing story of how the function of the HIV-1 protein called Nef was discovered and found to promote infection by excluding the host protein SERINC from virus particles. You can find TWiV #409 at microbe.tv/twiv, or listen below. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV409.mp3″] Click arrow to play Download TWiV 409 (75 MB .mp3, 124 min) …
Four years after filming ‘Threading the NEIDL’, Vincent and Alan return to the National Emerging Infectious Diseases Laboratory BSL4 facility at Boston University where they speak with science writer David Quammen. You can find TWiV #408 at microbe.tv/twiv, or watch/listen here. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV408.mp3″] Click arrow to play Download TWiV 408 (42 MB .mp3, 69 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV!
