Our discussion of influenza virus replication has so far brought us to the stage of viral RNA synthesis. Last time we discussed the formation of viral RNAs, an event which takes place in the cell nucleus. Now we’ll consider how these RNAs participate in the assembly of new infectious viral particles, as illustrated in the …
Although the new influenza H1N1 strain has been receiving a great deal of attention, apparently last season’s H1N1 and H3N2 strains continue to circulate, at least in the United States. FluView, the weekly surveillance report from the CDC, indicates that during weeks 17 and 18, seasonal influenza A (H1), A (H3), and B viruses are …
Co-circulation of three human influenza A subtypes Read More »
Here are answers to questions sent to virology blog about the new strain of influenza H1N1 that continues to spread globally. Q: Are you aware of efforts to make the virus strain nomenclature more informative? Understanding what segments/genes are related historically and sequence wise to what is confusing using the ‘serological’ definitions like H1N1. What …
Influenza A/Mexico/2009 (H1N1) – Questions & Answers Read More »
The influenza H1N1 outbreak in Mexico has been analyzed to provide information on the pandemic potential of the new virus strain. The estimates offer some insight into the transmissibility and severity of the virus but must be tempered with the understanding that there are still uncertainties about all aspects of the outbreak. Influenza incidence is …
Influenza A/Mexico/2009 (H1N1) virulence and transmission Read More »
Now that we have examined influenza viral RNA synthesis, it’s a good time to step back and look at a very important property of this step in viral replication. All nucleic acid polymerases insert incorrect nucleotides during chain elongation. This misincorporation is one of the major sources of diversity that allows viral evolution to take …
On episode #31 of the podcast “This Week in Virology”, Vincent, Dick, Alan, and Marc Pelletier summarize the past week’s influenza H1N1 activity, and discuss parvovirus infection of dogs and humans. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV031.mp3″] Click the arrow above to play, or right-click to download TWiV #31
