PACE

Trial By Error: Some Thoughts on Ten Years of Trial By Error

By David Tuller, DrPH Ten years ago this month, I launched Trial By Error with a 15,000-word investigation of the misbegotten and fraudulent PACE trial, which purported to prove that graded exercise therapy (GET) and cognitive behavior therapy (CBT) could cure what they then called chronic fatigue syndrome. And what an amazing ride it’s been …

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Trial By Error: A (Satirical) Field Guide to Conducting Biopsychosocial Research in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME)

By David Tuller, DrPH A reader from Belgium sent me the following (satirical) paper she’d written for the “Journal of Entrenched Paradigms.” I found it entertaining, well-written, and on-target, and figured others would as well. It offers a sharp assessment of some of the favorite methodological strategies of members of the CBT/GET ideological brigades. I …

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Trial By Error: BMJ Publishes New Propaganda Piece on Severe ME/CFS

By David Tuller, DrPH Last week, The BMJ published a commissioned propaganda piece—er, “opinion”—written by confirmed members of the cognitive behavior therapy/graded exercise therapy/Lightning Process ideological brigades. The title: “Patients with severe ME/CFS need hope and expert multidisciplinary care.” It repeats all the usual blah blah, along with the unwarranted assertions and evidence-free arguments about …

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Trial By Error: My Visits with Alem Matthees, 2025

By David Tuller, DrPH *This is a crowdfunding month at University of California, Berkeley. If you appreciate my work and would like to make a donation (tax-deductible to US taxpayers) to the university in support of my position, here’s the link: https://crowdfund.berkeley.edu/project/46120 ********** In 2018, I spent six weeks in Australia, visiting multiple cities on a …

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Trial By Error: A Reprise of a 2018 Post on My Visits with Alem Matthees

By David Tuller, DrPH In 2018, I spent six weeks in Australia, visiting multiple cities on a kind of ME/CFS tour around the country. Near the end, I spent five days in Perth. The local patient and advocacy organization arranged for me to give a talk, do some lobbying with local government, and so on. …

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Trial By Error: Our Presentation at the University of New South Wales

By David Tuller, DrPH On Tuesday, I gave a presentation at the Kirby Institute, a renowned research center at the University of New South Wales in Sydney, along with my friend and colleague Dr David Joffe, a respiratory medicine specialist. David spoke about the pathophysiology of Long Covid as well as the enormous economic burden of the …

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