A major goal of viral oncotherapy – the use of viruses to destroy tumors – is to design viruses that kill tumor cells but not normal cells. Two adenoviruses provide perfect examples of how this specificity can be achieved. Adenovirus CG0070, designed to treat bladder cancer, and adenovirus Oncorine, for head and neck tumors, replicate …
On episode #298 of the science show This Week in Virology, the TWiV gang answers follow-up questions about the Ebola virus outbreak in West Africa, then discuss treatment of disseminated multiple myeloma with oncolytic measles virus. You can find TWiV #298 at www.microbe.tv/twiv.
Hosts: Vincent Racaniello, Rich Condit, and Dickson Despommier Vincent, Rich, and Dickson review a meta-analysis on influenza vaccine, a killer virus in fungi that selects against RNAi, and the use of armed and targeted poxviruses for oncolytic virotherapy. Please help us by taking our listener survey. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV156.mp3″] Click the arrow above to play, or right-click …
TWiV 156: Armed and targeted killer meta-analysis Read More »
Hosts: Vincent Racaniello, Rich Condit, and Alan Dove Vincent, Rich, and Alan discuss a method for identifying viruses of individual environmental bacteria, and the using a picornavirus for oncotherapy. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV142.mp3″] Click the arrow above to play, or right-click to download TWiV 142 (69 MB .mp3, 95 minutes). Subscribe to TWiV (free) in iTunes , at …
